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2.
Rev. méd. Chile ; 129(2): 196-200, feb. 2001. ilus
Article in Spanish | LILACS | ID: lil-284988

ABSTRACT

Mediastinitis with graft infection is a serious complication of ascending aorta replacement. We report two cases of graft infection, treated with surgical cleaning, graft preservation and transposition of muscle flaps. A 62 years old male was admitted 34 days after an ascending aortic grafting due to a sternal dehiscence and mediastinitis. Antimicrobial treatment was started and a surgical cleaning performed, leaving an open sternotomy. Three days later, the thoracic cavity was closed with a rectus abdominis muscle flap. After 23 months of follow up, the patient is well and without evidence of infection. A 74 years old male was subjected to an aortic valve and ascending aorta replacement and a myocardial revascularization. In the postoperative period, the patient developed septic signs, and a purulent drainage. A CAT scan showed a liquid collection surrounding the aortic graft. On tW Sixteenth postoperative day, a surgical cleaning was performed and the thorax was closed with the pectoralis major muscle. After 10 months of follow up, the patient is in Good condition and without evidence of infection


Subject(s)
Humans , Male , Middle Aged , Aorta/microbiology , Prosthesis-Related Infections/therapy , Heart Valve Prosthesis/microbiology , Graft Survival/immunology , Mediastinitis/microbiology , Obesity/complications , Surgical Flaps , Systemic Inflammatory Response Syndrome/therapy
3.
Arch. Inst. Cardiol. Méx ; 67(1): 17-23, ene.-feb. 1997. ilus
Article in Spanish | LILACS | ID: lil-195860

ABSTRACT

Aunque los factores aterogénicos más importantes han sido extensamente estudiados, hay otros más cuya verdadera importancia causal no ha sido bien definida. Existen evidencias patológicas e inmunológicas acerca del papel de diversos agentes infecciosos en la génesis o el desarrollo de la aterosclerosis. Recientemente se ha ligado a la Chlamydia pneumoniae con la aterogénesis al encontrarse evidencia inmunológica de la presencia de este germen en lesiones ateromatosas humana. Se estudiaron 16 especímenes de aortas, obtenidos en autopsias de individuos muertos por cardiopatía isquémica. Se determinó la infección de Ch. pneumoniae, mediante una técnica de inmunofluorescencia con anticuerpo monoclonal murino específico. La reacción positiva se encontró en placas fibrolípidas avanzadas, no ulceradas, de dos pacientes (13 por ciento), incidencia comparable a la informada en la literatura mundial. No se conoce cuál es la verdadera relación entre la infección y la aterogénesis y si la primera comienza o agrava el proceso ateroscleroso o es un fenómeno independiente del proceso arterial.


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Aorta/microbiology , Aorta/pathology , Atherosclerosis/etiology , Chlamydophila pneumoniae/pathogenicity , Fluorescent Antibody Technique
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